Progetto integrato tra Università, enti privati operanti nel trasferimento tecnologico, enti pubblici per la promozione di nuove professionalità e imprenditorialità

Funding programme: FSE Fondo Sociale Europeo
Start – end year: 2002 – 2003

Partnership di Biotecnologie e Bioscienze, Università di Milano-Bicocca
Biopolo S.c.r.l.
Comune di Bresso (MI)
Consorzio Milano Ricerche

The project

The Project fostered technological matters and exploited IT targeted to the biopharmaceutical sector, foreseeing these main activities:

  1. development of platforms for biopharmaceuticals:
    • set up of tools for modelling of 3D proteins structures and selection of protein receptor sites,
    • generation of virtual libraries section and evaluation of molecular descriptors,
    • docking energies evaluation,
    • application of a bayesian network model for the virtual libraries data analysis;
  2. development of the DIA-BAYES diagnostic platform:
    • selection of the best computational model for statistic analysis and inference of molecular docking data provided by DELOS and integration of the BAYES library elements,
    • design of clinical database structure most suitable to its use in integrated systems of clinical/diagnostic data statistical inference,
    • extraction and systematisation of the BAYES library elements to set up the expert system targeted to the clinical data analysis and to the subsequent diagnostic inference,
    • experimentation and validation of DIA-BAYES upon clinical cases library, already (2004) available and reliable for a long time period;
  3. vocational training path for biopharmaceutical industries and hospital representatives;
  4. design and realisation of a range of multimedia tools for presenting new information science methodologies for the biopharmaceutical research and the support to the medical diagnosis.

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